Scientists have created E. coli kamikaze, killing microbes

Sep 9, 2011



Singapore scientists have created a strain of E. coli that can recognize and destroy common pathogens severe nosocomial infections - Pseudomonas aeruginosa

Pseudomonas aeruginosa (Pseudomonas aeruginosa) frequently affects compromised patients, causing severe sepsis. Circulating in the hospital, this bacterium has acquired resistance to most common antibiotics, says Medportal.

Researchers from Anyang Technological University, decided to modify it to combat Pseudomonas infection non pathogenic strain of E. coli, which is a normal component of the intestinal micro flora.

For this purpose, bacteria were embedded DNA genes in the presence of Pseudomonas aeruginosa producing specific toxins in relation to it, and then destroy the cage of the modified E. coli to release this toxin.

As explained study leader Matthew Wok Chang, under experimental conditions "bacterium kamikaze" inhibited the growth of Pseudomonas aeruginosa to 90 percent. According to him, microbial "Detector" easy change “tunes" it to recognize other bacteria such as Vibrato cholera.

Researchers believe that they have developed E. coli can be administered in the form of food such as yogurt. They are currently conducting trials of the drug on animals. According to the authors of the project, the method can also be used to combat other microbes.

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